His struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease and of humans with creutzfeldt jakob disease had been waged largely alone and in some cases in the face of strenuous disagreementin this book prusiner tells the remarkable story of his discovery of prions infectious . Madness and memory the discovery of prions a new biological principle of disease in 1997 stanley b prusiner received a nobel prize the worlds most prestigious award for achievement in physiology or medicine that he was the sole recipient of the award for the year was entirely appropriate his struggle to identify the agent responsible for . This item madness and memory the discovery of prions a new biological principle of disease by stanley b prusiner hardcover 2544 only 1 left in stock order soon ships from and sold by incofan. Madness and memory the discovery of prions a new biological principle of disease stanley b prusiner 9780300191141 books amazonca. In madness and memory prusiner recounts the journey to his remarkable discovery of prions infectious proteins that replicate and cause disease but surprisingly contain no genetic material along the way he sheds light on the world of contemporary science and the meticulousness and perseverance it requires